Overview

I am a Research fellow at the EPSRC Centre for Predictive Modeling in Heathcare.

My research interestes lie in the areas of compuational biology, biological physics, and statistical systems biology. I am particularly interested in how living systems at different scales of organisation (from biomolecules to cells to tissues and organs) process information: sensing and responding to external cues. I pursue these questions in the fields of cell biology, endocrinology and neuroendocrinology.

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Publications

_{Copyright Notice: Any articles made available for download are for personal use only. Any other use requires prior permission of the author and the copyright holder.}

| 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2010 | 2009 | 2008 | 2006 |

2024

• Ivanova D, Voliotis M, Tsaneva‐Atanasova K, O'Byrne KT, Li X. (2024) NK3R signalling in the posterodorsal medial amygdala is involved in stress‐induced suppression of pulsatile LH secretion in female mice, Journal of Neuroendocrinology, DOI:10.1111/jne.13384. [PDF]
• Voliotis M, Abbara A, Prague JK, Veldhuis JD, Dhillo WS, Tsaneva-Atanasova K. (2024) HormoneBayes: A novel Bayesian framework for the analysis of pulsatile hormone dynamics, PLOS Computational Biology, volume 20, no. 2, pages e1011928-e1011928, DOI:10.1371/journal.pcbi.1011928. [PDF]
• Hanassab S, Abbara A, Yeung AC, Voliotis M, Tsaneva-Atanasova K, Kelsey TW, Trew GH, Nelson SM, Heinis T, Dhillo WS. (2024) The prospect of artificial intelligence to personalize assisted reproductive technology, npj Digital Medicine, volume 7, no. 1, article no. 55, DOI:10.1038/s41746-024-01006-x. [PDF]
• Qiu J, Voliotis M, Bosch MA, Li XF, Zweifel LS, Tsaneva-Atanasova K, O’Byrne KT, Rønnekleiv OK, Kelly MJ. (2024) Estradiol elicits distinct firing patterns in arcuate nucleus kisspeptin neurons of females through altering ion channel conductances, DOI:10.1101/2024.02.20.581121. [PDF]
• Nechyporenko K, Voliotis M, Li XF, Hollings O, Ivanova D, Walker JJ, O’Byrne KT, Tsaneva-Atanasova K. (2024) Neuronal Network Dynamics in the Posterodorsal Amygdala: Shaping Reproductive Hormone Pulsatility, DOI:10.1101/2024.01.21.574304. [PDF]
• Abbara A, Adams S, Phylactou M, Izzi-Engbeaya C, Mills EG, Thurston L, Koysombat K, Hanassab S, Heinis T, Tan TM-M. (2024) Quantifying the variability in the assessment of reproductive hormone levels, Fertil Steril, volume 121, no. 2, pages 334-345, DOI:10.1016/j.fertnstert.2023.11.010. [PDF]

2023

• Madsen RR, Le Marois A, Mruk O, Voliotis M, Yin S, Sufi J, Qin X, Zhao SJ, Gorczynska J, Morelli D. (2023) Oncogenic PIK3CA corrupts growth factor signaling specificity, DOI:10.1101/2023.12.23.573207.
• Zhang B, Phetsang W, Stone MRL, Kc S, Butler MS, Cooper MA, Elliott AG, Łapińska U, Voliotis M, Tsaneva-Atanasova K. (2023) Synthesis of vancomycin fluorescent probes that retain antimicrobial activity, identify Gram-positive bacteria, and detect Gram-negative outer membrane damage, Commun Biol, volume 6, no. 1, DOI:10.1038/s42003-023-04745-x. [PDF]

2022

• Adams S, Voliotis M, Phylactou M, Izzi-Engbeaya C, Mills E, Thurston L, Hanassab S, Tsaneva-Atanasova K, Heinis T, Comninos A. (2022) Quantifying the Variability in the Outpatient Assessment of Reproductive Hormone levels, Endocrine Abstracts, DOI:10.1530/endoabs.86.p117.
• Voliotis M, Abbara A, Prague JK, Veldhuis JD, Dhilo WS, Tsaneva-Atanasova K. (2022) LBMON233 Hormonebayes: A Novel Bayesian Toolbox For Analysis Of Pulsatile Hormone Dynamics, Journal of the Endocrine Society, volume 6, no. Supplement_1, pages a648-a649, DOI:10.1210/jendso/bvac150.1341.
• Lass G, Li XF, Voliotis M, Wall E, de Burgh RA, Ivanova D, McIntyre C, Lin X, Colledge WH, Lightman SL. (2022) GnRH pulse generator frequency is modulated by kisspeptin and GABA‐glutamate interactions in the posterodorsal medial amygdala in female mice, Journal of Neuroendocrinology, volume 34, no. 11, DOI:10.1111/jne.13207. [PDF]
• Voliotis M, Hanassab S, Abbara A, Heinis T, Dhillo WS, Tsaneva-Atanasova K. (2022) Quantitative approaches in clinical reproductive endocrinology, Current Opinion in Endocrine and Metabolic Research, volume 27, pages 100421-100421, article no. 100421, DOI:10.1016/j.coemr.2022.100421. [PDF]
• Plain Z, Voliotis M, McArdle CA, Tsaneva-Atanasova K. (2022) Modelling KNDy neurons and gonadotropin-releasing hormone pulse generation, Current Opinion in Endocrine and Metabolic Research, volume 27, pages 100407-100407, article no. 100407, DOI:10.1016/j.coemr.2022.100407. [PDF]
• Voliotis M, Rosko J, Pilizota T, Liverpool TB. (2022) Steady-state running rate sets the speed and accuracy of accumulation of swimming bacteria, Biophys J, volume 121, no. 18, pages 3435-3444, DOI:10.1016/j.bpj.2022.08.012. [PDF]
• Łapińska U, Voliotis M, Lee KK, Campey A, Stone MRL, Tuck B, Phetsang W, Zhang B, Tsaneva-Atanasova K, Blaskovich MAT. (2022) Fast bacterial growth reduces antibiotic accumulation and efficacy, eLife, volume 11, DOI:10.7554/elife.74062. [PDF]
• Glover G, Voliotis M, Łapińska U, Invergo BM, Soanes D, O’Neill P, Moore K, Nikolic N, Petrov PG, Milner DS. (2022) Nutrient and salt depletion synergistically boosts glucose metabolism in individual Escherichia coli cells, Communications Biology, volume 5, no. 1, article no. 385, DOI:10.1038/s42003-022-03336-6. [PDF]
• Voliotis M, Abbara A, Prague JK, Veldhuis JD, Dhillo WS, Tsaneva-Atanasova K. (2022) HormoneBayes: a novel Bayesian framework for the analysis of pulsatile hormone dynamics, DOI:10.1101/2022.03.14.22272000. [PDF]
• Glover G, Voliotis M, Łapińska U, Invergo BM, Soanes D, O’Neill P, Moore K, Nikolic N, Petrov PG, Milner DS. (2022) Nutrient and salt depletion synergistically boosts glucose metabolism in individual bacteria, DOI:10.1101/2022.01.26.477826.
• Voliotis M, Plain Z, Li XF, McArdle CA, O’Byrne KT, Tsaneva‐Atanasova K. (2022) Mathematical models in GnRH research, Journal of Neuroendocrinology, volume 34, no. 5, DOI:10.1111/jne.13085.

2021

• Voliotis M, Li XF, De Burgh R, Lass G, Ivanova D, McIntyre C, O’Byrne KT, Tsaneva-Atanasova K. (2021) Modulation of pulsatile GnRH dynamics across the ovarian cycle: the role of glutamatergic transmission in the arcuate kisspeptin network, DOI:10.1101/2021.03.22.436428.
• Voliotis M, Li XF, De Burgh RA, Lass G, Ivanova D, McIntyre C, O'Byrne K, Tsaneva-Atanasova K. (2021) Modulation of pulsatile GnRH dynamics across the ovarian cycle via changes in the network excitability and basal activity of the arcuate kisspeptin network, Elife, volume 10, DOI:10.7554/eLife.71252. [PDF]
• Łapińska U, Voliotis M, Lee KK, Campey A, Stone MRL, Phetsang W, Zhang B, Tsaneva-Atanasova K, Blaskovich MAT, Pagliara S. (2021) Fast bacterial growth reduces antibiotic accumulation and efficacy, DOI:10.1101/2021.10.18.464851. [PDF]
• McArdle CA, Voliotis M, Tsaneva-Atanasova K, Fowkes RC. (2021) Chapter 7 - Gonadotropin-Releasing Hormone Receptors and Signaling, Cellular Endocrinology in Health and Disease (Second Edition), Academic Press, 149-181, DOI:10.1016/B978-0-12-819801-8.00007-7. [PDF]

2020

• Abbara A, Eng PC, Phylactou M, Clarke SA, Richardson R, Sykes CM, Phumsatitpong C, Mills E, Modi M, Izzi-Engbeaya C. (2020) Kisspeptin receptor agonist has therapeutic potential for female reproductive disorders, J Clin Invest, volume 130, no. 12, DOI:10.1172/JCI139681. [PDF]
• Zavala E, Voliotis M, Zerenner T, Tabak J, Walker JJ, Li XF, Terry JR, Lightman SL, O’Byrne K, Tsaneva-Atanasova K. (2020) Dynamic Hormone Control of Stress and Fertility, Frontiers in Physiology, volume 11, pages 1457-1457, DOI:10.3389/fphys.2020.598845. [PDF]
• Zavala E, Voliotis M, Zerenner T, Tabak J, Walker JJ, Li XF, Terry JR, Lightman SL, O’Byrne K, Tsaneva-Atanasova K. (2020) Dynamic hormone control of stress and fertility, DOI:10.1101/2020.08.24.264234. [PDF]
• Pope RJP, Garner KL, Voliotis M, Lay AC, Betin VMS, Tsaneva-Atanasova K, Welsh GI, Coward RJM, McArdle CA. (2020) An information theoretic approach to insulin sensing by human kidney podocytes, Molecular and Cellular Endocrinology, pages 110976-110976, DOI:10.1016/j.mce.2020.110976. [PDF]
• Voliotis M, Rosko J, Pilizota T, Liverpool T. (2020) Steady state running rate sets the speed and accuracy of accumulation of swimming bacterial populations. [PDF]
• Voliotis M. (2020) Single-cell microfluidics facilitates the rapid quantification of antibiotic accumulation in Gram-negative bacteria. (Model & Matlab Code).
• Cama J, Voliotis M, Metz J, Smith A, Iannucci J, Keyser UF, Tsaneva K, Pagliara S. (2020) Single-cell microfluidics facilitates the rapid quantification of antibiotic accumulation in Gram-negative bacteria, Lab on a Chip, DOI:10.1039/D0LC00242A.

2019

• Dhillo W, Prague J, Voliotis M, Clarke S, Comninos A, Abbara A, Jayasena C, Roberts R, Yang L, Veldhuis J. (2019) OR11-4 Determining the Relationship between Hot Flushes and LH Pulses in Menopausal Women Using Mathematical Modelling, Journal of the Endocrine Society, volume 3, no. Supplement_1, pages or11-or14, DOI:10.1210/js.2019-or11-4.
• Dhillo W, Liang S, Kinghorn A, Voliotis M, Prague J, Veldhuis J, Tsaneva-Atanasova K, McArdle C, Li HWR, Cass T. (2019) SAT-LB040 Measuring LH Pulsatility in Patients with Reproductive Disorders Using a Novel Robotic Aptamer-Enabled Electrochemical Reader (RAPTER), Journal of the Endocrine Society, volume 3, no. Supplement_1, DOI:10.1210/js.2019-sat-lb040. [PDF]
• Voliotis M, Feng Li X, De Burgh R, Lass G, Lightman SL, O’Byrne KT, Tsaneva-Atanasova K. (2019) The origin of GnRH pulse generation: An integrative mathematical-experimental approach, Journal of Neuroscience, DOI:10.1523/JNEUROSCI.0828-19.2019. [PDF]
• Dhillo W, Liang S, Kinghorn A, Voliotis M, Prague J, Veldhuis J, Tsaneva-Atanasova K, McArdle C, Li R, Cass A. (2019) Measuring LH Pulsatility in Patients with Reproductive Disorders Using a Novel Robotic Aptamer-Enabled Electrochemical Reader (RAPTER), HUMAN REPRODUCTION, volume 34, pages 125-126. [PDF]
• Cama J, Voliotis M, Metz J, Smith A, Iannucci J, Keyser UF, Tsaneva-Atanasova K, Pagliara S. (2019) Antibiotic transport kinetics in Gram-negative bacteria revealed via single-cell uptake analysis and mathematical modelling, DOI:10.1101/645507. [PDF]
• Prague JK, Voliotis M, Clarke S, Comninos AN, Abbara A, Jayasena CN, Roberts RE, Yang L, Veldhuis JD, Tsaneva-Atanasova K. (2019) Determining the relationship between hot flushes and LH pulses in menopausal women using mathematical modelling, The Journal of Clinical Endocrinology & Metabolism, DOI:10.1210/jc.2018-02797.
• Liang S, Kinghorn AB, Voliotis M, Prague JK, Veldhuis JD, Tsaneva-Atanasova K, McArdle CA, Li RHW, Cass AEG, Dhillo WS. (2019) Measuring luteinising hormone pulsatility with a robotic aptamer-enabled electrochemical reader, Nature Communications, volume 10, no. 1, DOI:10.1038/s41467-019-08799-6. [PDF]
• Zavala E, Wedgwood KCA, Voliotis M, Tabak J, Spiga F, Lightman SL, Tsaneva-Atanasova K. (2019) Mathematical Modelling of Endocrine Systems, volume 30, pages 244-257, article no. 4, DOI:10.1016/j.tem.2019.01.008.

2018

• Alobaid H, Voliotis M, Tsaneva-Atanasova K, McArdle C. (2018) Measuring of information transfer via gonadotropin-releasing hormone receptors (GnRHR) shows a remarkable loss of information through signalling, Endocrine Abstracts, DOI:10.1530/endoabs.59.p130.
• Voliotis M, Li XF, De Burgh R, Lass G, Lightman SL, O’Byrne KT, Tsaneva-Atanasova K. (2018) Mathematical modelling elucidates core mechanisms underpinning GnRH pulse generation, DOI:10.1101/245548. [PDF]
• Voliotis M, Garner KL, Alobaid H, Tsaneva-Atanasova K, McArdle CA. (2018) Exploring Dynamics and Noise in Gonadotropin-Releasing Hormone (GnRH) Signaling, United States, 405-429, DOI:10.1007/978-1-4939-8618-7_19. [PDF]

2017

• Pratap A, Garner KL, Voliotis M, Tsaneva-Atanasova K, McArdle CA. (2017) Authors response to communication about mathematical modeling of gonadotropin-releasing hormone signaling, Molecular and Cellular Endocrinology, DOI:10.1016/j.mce.2017.09.035. [PDF]
• Voliotis M, Garner KL, Alobaid H, Tsaneva-Atanasova K, McArdle CA. (2017) Gonadotropin-releasing hormone signaling: An information theoretic approach, Molecular and Cellular Endocrinology, volume 463, pages 106-115, DOI:10.1016/j.mce.2017.07.028. [PDF]
• Voliotis M, Garner KL, Alobaid H, Tsaneva-Atanasova K, McArdle CA. (2017) Mutual information estimation - MATLAB code.
• Granados AA, Crane MM, Montano-Gutierrez LF, Tanaka RJ, Voliotis M, Swain PS. (2017) Distributing tasks via multiple input pathways increases cellular survival in stress, Elife, volume 6, DOI:10.7554/eLife.21415. [PDF]
• Voliotis M, Liverpool TB. (2017) Statistical mechanics of tuned cell signalling: Sensitive collective response by synthetic biological circuits, Journal of Statistical Mechanics: Theory and Experiment, volume 2017, no. 3, DOI:10.1088/1742-5468/aa58ad.
• Garner KL, Voliotis M, Alobaid H, Perrett RM, Pham T, Tsaneva-Atanasova K, McArdle CA. (2017) Information Transfer via Gonadotropin-Releasing Hormone Receptors to ERK and NFAT: Sensing GnRH and Sensing Dynamics, Journal of the Endocrine Society, volume 1, pages 260-277, article no. 4, DOI:10.1210/js.2016-1096.
• Pratap A, Garner KL, Voliotis M, Tsaneva-Atanasova K, McArdle CA. (2017) Mathematical modeling of gonadotropin-releasing hormone signaling, Mol Cell Endocrinol, volume 449, pages 42-55, DOI:10.1016/j.mce.2016.08.022. [PDF]

2016

• Cohen N, Jordan J, Voliotis M. (2016) Preferential duplication graphs, Journal of Applied Probability, volume 47, no. 2, pages 572-585, DOI:10.1017/s0021900200006823.
• Garner KL, Perrett RM, Voliotis M, Bowsher C, Pope GR, Pham T, Caunt CJ, Tsaneva-Atanasova K, McArdle CA. (2016) Information Transfer in Gonadotropin-releasing Hormone (GnRH) Signaling, Journal of Biological Chemistry, volume 291, no. 5, pages 2246-2259, DOI:10.1074/jbc.m115.686964. [PDF]

2015

• Garner K, Perrett R, Voliotis M, Pham T, Tsaneva-Atanasova K, McArdle C. (2015) An information theoretic approach to GnRH signalling, Endocrine Abstracts, DOI:10.1530/endoabs.37.ep163.
• Garner K, Perrett R, Voliotis M, Pham T, Tsaneva-Atanasova K, McArdle C. (2015) Information transfer in GnRH signalling: ERK-mediated feedback loops control hormone sensing, Endocrine Abstracts, DOI:10.1530/endoabs.38.p359.
• Voliotis M, Thomas P, Grima R, Bowsher CG. (2015) Stochastic Simulation of Biomolecular Networks in Dynamic Environments, DOI:10.48550/arxiv.1511.01268.
• Voliotis M. (2015) Toy model of ERK signalling, DOI:10.1074/jbc.M115.686964.
• Voliotis M, Thomas P, Grima R, Bowsher CG. (2015) Stochastic Simulation of Biomolecular Networks in Dynamic Environments. [PDF]

2014

• Bowsher CG, Voliotis M. (2014) Mutual Information and Conditional Mean Prediction Error, DOI:10.48550/arxiv.1407.7165.
• Voliotis M, Perrett RM, McWilliams C, McArdle CA, Bowsher CG. (2014) Information transfer by leaky, heterogeneous, protein kinase signaling systems, Proc Natl Acad Sci U S A, volume 111, no. 3, pages E326-E333, DOI:10.1073/pnas.1314446111. [PDF]
• Bowsher CG, Voliotis M. (2014) Mutual Information and Conditional Mean Prediction Error. [PDF]
• Perrett R, Voliotis M, Armstrong S, Pope G, Tsaneva-Atanasova K, McArdle C. (2014) Systems approaches to understanding GnRH signalling, Endocrine Abstracts, volume 34, DOI:10.1530/endoabs.34.S1.1.
• Perrett RM, Voliotis M, Armstrong SP, Fowkes RC, Pope GR, Tsaneva-Atanasova K, McArdle CA. (2014) Pulsatile Hormonal Signaling to Extracellular Signal-Regulated Kinase: Exploring System Sensitivity to Gonadotropin-Releasing Hormone Pulse Frequency and Width, Journal of Biological Chemistry, volume 289(11), pages 7873-7883, DOI:10.1074/jbc.M113.532473.

2013

• Bowsher CG, Voliotis M, Swain PS. (2013) The Fidelity of Dynamic Signaling by Noisy Biomolecular Networks, PLoS Computational Biology, volume 9, no. 3, DOI:10.1371/journal.pcbi.1002965.

2012

• Voliotis M, Cohen N, Molina-París C, Liverpool TB. (2012) Proofreading of misincorporated nucleotides in DNA transcription, Physical Biology, volume 9, no. 3, DOI:10.1088/1478-3975/9/3/036002.
• Voliotis M, Cohen N, Molina-París C, Liverpool TB. (2012) Proofreading of misincorporated nucleotides in DNA transcription, Physical Biology, volume 9, no. 3, DOI:10.1088/1478-3975/9/3/036007.
• Voliotis M, Bowsher CG. (2012) The magnitude and colour of noise in genetic negative feedback systems, Nucleic Acids Research, volume 40, no. 15, pages 7084-7095, DOI:10.1093/nar/gks385.

2010

• Cohen N, Jordan J, Voliotis M. (2010) Preferential duplication graphs, Journal of Applied Probability, volume 47, no. 2, pages 572-585, DOI:10.1239/jap/1276784910.

2009

• Voliotis M, Cohen N, Molina-París C, Liverpool TB. (2009) Backtracking and proofreading in DNA transcription, Physical Review Letters, volume 102, no. 25, DOI:10.1103/PhysRevLett.102.258101.

2008

• Voliotis M, Cohen N, Molina-París C, Liverpool TB. (2008) Fluctuations, pauses, and backtracking in DNA transcription, Biophysical Journal, volume 94, no. 2, pages 334-348, DOI:10.1529/biophysj.107.105767.

2006

• Voliotis M, París CM, Tanniemola LB, Cohen N. (2006) Noise R Us: From gene regulatory networks to WWW, Proceedings of AISB'06: Adaptation in Artificial and Biological Systems, volume 3, pages 167-175.

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